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Rewarding for you and us Defeat Diabetes Foundation Defeat Diabetes
Foundation 150 153rd Ave, Suite 300 Madeira Beach, FL 33708 |
Intensively Managed Diabetes Costs $28,661 More Then Conventional TreatmentPosted: Wednesday, January 10, 2007Even at $28,000 more, the health care system says it represents a good value. Improved Glycemic Control: Intensive insulin therapy, as practiced in the Diabetes Control and Complications Trial, was more costly by $28,661 per year of life saved than was conventional management, but it represents a good value from a health care system perspective.1,2 In a managed care setting, with higher charges associated with increasing HbA1c and cardiac morbidities, health care costs for diabetes could be trimmed by $400 to $4,000 per person over a three-year period for each 1% reduction in HbA1c.3 Shetty et al. reported that patients achieving HbA1c 7% or lower incurred 32% lower health care costs in the follow-up year than when this target was not met.3 In another example, achieving glycemic control improved symptoms, general perceived health, and cognitive functioning, translating to average savings of $91 per worker per month attributable to less absenteeism, $304 per 1,000 person-days attributable to fewer hospital-bed-days, and $1,615 per 1,000 person-days attributable to reduced restricted-activity-days.4 Improving HbA1c by 1% or more for sustained periods eventually saved one health maintenance organization between $685 and $950 per patient per year, despite higher costs for primary care visits in the first year.5 A meta-analysis of four trials that used insulin detemir based basal/bolus regimens yielded an incremental cost-effectiveness ratio of $36,284 per quality-adjusted life-years (QALY) gained, a good value by international health care standards.6 In another health economic evaluation of insulin glargine and NPH insulin that projected lifetime direct drug and complications costs, insulin glargine was found to be clinically beneficial and more cost-effective than NPH insulin. Although NPH insulin was less expensive, insulin glargine treated patients experienced less hypoglycemia at lower HbA1c values, gaining 0.07 QALY at $23,717 per QALY and 0.23 QALY at $9,804 per QALY in patients with type 1 and type 2 diabetes, respectively.7
1. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993;329:977-986.
2. Lifetime benefits and costs of intensive therapy as practiced in the diabetes control and complications trial. The Diabetes Control and Complications Trial Research Group. JAMA . 1996;276:1409-1415. 3. Gilmer TP, O'Connor PJ, Manning WG, Rush WA. The cost to health plans of poor glycemic control. Diabetes Care. 1997;20:1847-1853. 4. Testa MA, Simonson DC. Health economic benefits and quality of life during improved glycemic control in patients with type 2 diabetes mellitus: a randomized, controlled, double-blind trial. JAMA. 1998;280:1490-1496. 5. Wagner EH, Sandhu N, Newton KM, et al. Effect of improved glycemic control on health care costs and utilization. JAMA. 2001;285:182-189. 6. Palmer AJ, Roze S, Valentine WJ, et al. Cost-effectiveness of detemir-based basal/bolus therapy versus NPH-based basal/bolus therapy for type 1 diabetes in a UK setting: an economic analysis based on meta-analysis results of four clinical trials. Curr Med Res Opin. 2004;20:1729-1746. 7. Thompson M, Sauriol L, Grima D. Health economic evaluation of insulin glargine for the treatment of type-1 and type-2 diabetes [abstract]. Value Health. 2005;8:A163.
Source: Diabetes In Control |
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