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Diabetic Men Have Lower Risk of Prostate Cancer

Posted: Thursday, March 29, 2007

As epidemiologic evidence suggests diabetic men have a slightly lower prostate cancer risk than non-diabetic men.

Seattle researchers examined this association in a prospective cohort study of 35 239 men, 50–76 years old, in Washington State who completed a baseline questionnaire between 2000 and 2002. Incident prostate cancers as of 31 December 2004 were identified through the SEER registry.

They found that diabetic men had a slightly lower risk of prostate cancer than non-diabetic men (hazard ratio (HR) 0.83). Insulin users overall and insulin users with diabetic complications had decreased risks, compared to non-diabetic men (HR 0.49) and (HR 0.36), respectively. Oral medication use for diabetes was not associated with prostate cancer. Insulin is likely a marker of severity of diabetes.

The researchers concluded: “Future studies of this association should consider diabetes type, treatment, severity, complications and biomarkers”

An interesting association that might be somewhat reassuring for diabetic men.

Source: Diabetes In Control: Diabetes and the risk of prostate cancer: the role of diabetes treatment and complications, C M Velicer, S Dublin and E White. Category Y. Male Genital System, Breast, U. Urinary System.. Posted on Global Family Doctor 22 March 2007