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Short Women at Greater Risk for Gestational Diabetes

Posted: Friday, November 20, 2009

Caucasian women with GDM are shorter than pregnant women without GDM regardless of the diagnostic criteria used or the severity of glucose intolerance.

Although height is an independent predictor for GDM, its predictive value for identifying women at risk is relatively low and should not be considered in selective screening for this disease.

The aim of the study was to assess the influence of height variations on the risk of gestational diabetes (GDM).

In the study, 1,830 Caucasian women with GDM and 1,011 healthy pregnant women were analyzed.The following data were collected: age, prior macrosomia, prior GDM, parity, history of Type 2 diabetes in first degree relatives,weight before pregnancy, weight gain during pregnancy, glucose level at the first obstetric visit, results of the glucose challenge test and oral glucose tolerance test, glycated hemoglobin and method for treatment of GDM.

The results showed that women with GDM were significantly shorter than the healthy controls (165.7 ± 5.6 vs. 163.8±6.6 cm;P<0.001). The differences of height were not significant between GDM women who required insulin therapy and those treated with diet alone (P=0.12). All the studied variables, including height, were independently associated with GDM. Even after adjustment for confounding variables, height was still associated with GDM (OR 0.958, 95%CI: 0.94–0.97; P<0.00001). In women with GDM diagnosed by 75 g oral glucose tolerance test a significant inverse association was found of height adjusted for age and pregravid weight with 2-h glucose level (â= -0.12;P<0.0001).

From the results it was concluded that Caucasian women with GDM are shorter than pregnant women without GDM regardless of the diagnostic criteria used or the severity of glucose intolerance. Although height is an independent predictor for GDM, its predictive value for identifying women at risk is relatively low and should not be considered in selective screening for this disease.

Source: Diabetes In Control

 
 
 
 
 
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