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Aspirin Use Linked to a Lower Risk of Diabetes

Posted: Wednesday, May 06, 2009

Results of a new study recently published suggest an association between aspirin use and a decreased risk of developing Type 2 diabetes.

Dr. Yasuaki Hayashino, of the University Graduate School of Medicine, Kyoto, Japan, stated that, "Analytic studies on aspirin or non-aspirin NSAIDs and the risk of diabetes in free-living human populations are limited."

To investigate, the researchers analyzed data from the Physicians Health Study, which included 22,071 apparently healthy male physicians, and has accumulated 22 years of follow-up data.

The participants self-reported their history of diabetes, aspirin use, and various lifestyle factors at baseline and in yearly follow-up questionnaires.

A total of 1,719 cases of diabetes were reported during follow-up. Subjects who self-selected any aspirin had a multivariable-adjusted hazard ratio of developing diabetes of 0.86, compared to those that did not take aspirin.

Non-aspirin NSAIDs were not associated with a decreased risk of developing diabetes.

"Decreased risk of Type 2 diabetes may be added to the list of clinical benefits of aspirin," Dr. Hayashino and colleagues conclude. "Future studies are warranted to further investigate this association."

Source: Diabetes In Control: Am J Med 2009;122:374-379.