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Anti-inflammatory Drugs and Diabetic Retinopathy: Aspirin Inhibits Diabetic Retinopathy in Animals.

Posted: Wednesday, April 25, 2007

The potential of three different salicylates to inhibit diabetes-induced degeneration of retinal capillaries in rats has now been tested.
 
The results indicate that the salicylate-mediated inhibition of the degeneration of retinal capillaries and of the retinas of diabetic animals is mediated, at least in part, via inhibition of nuclear factor kappa B and the subsequent inflammatory response.
 
Salicylates can be expected to provide further insights into the pathogenesis of diabetic retinopathy and to offer a basis for the development of even better therapies. 

Source: Diabetes In Control: Diabetes,56 (337-345): Zheng L, Howell S, Hatala D, Huang K, Kern T Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy.

 
 
 
 
 
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