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Diabetes In Pregnancy Increases Children's Diabetes Risk

Posted: Thursday, March 06, 2008

Researchers have identified a link between the occurrence of type 2 diabetes in adults and the presence of type 1 diabetes or pregnancy-related diabetes in their mothers.

Dr. Tine Dalsgaard Clausen of Copenhagen University Hospital and colleagues there and elsewhere tested 597 Danish adults for diabetes or conditions that might lead to diabetes.

The likelihood of having type 2 diabetes or pre-diabetes was related to the mother's diabetes status during pregnancy, the investigators report in the medical journal Diabetes Care.

Specifically, the rate of diabetes or pre-diabetes was 21 percent in subjects born to mothers who had pregnancy-related diabetes (termed gestational diabetes), 12 percent in those whose mothers had a genetic predisposition for diabetes, 11 percent when the mothers had type 1 diabetes, and 4 percent in subjects born to women with no history of gestational or other types of diabetes.

The findings support the idea that exposure to high blood sugar levels in the womb contributes to the development of type 2 diabetes in adulthood, the researchers conclude. Aiming for normal blood glucose levels in pregnant women "may reduce the risk of type 2 diabetes in future generations."

Source: Diabetes In Control: Diabetes Care, February 2008.