Three different protocols were employed to test Aprise. In the first protocol rapid glucose variations were induced by venous infusion of dextrose solution and insulin. In the second protocol, the glucose level was increased by drinking a glucose solution and decreased by the diabetic subject's regular medications. And in the third protocol the glucose level was raised with a regular meal and decreased again by the diabetic subject's regular medications. Thirty subjects participated in the studies. The prospective results were a Mean Absolute Relative Deviation of 19%," explained Dr. Benny Pesach.