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Complications » Cardiovascular

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Tight Blood Pressure Control Not Supported in Patients with Diabetes and Coronary Artery Disease
Posted: Sunday, March 28, 2010
Current blood pressure (BP) guidelines for individuals with diabetes (systolic BP [SBP] <130 mm Hg) based on the notion that lower is better were not supported by results of the International Verapamil SR-Trandolapril (INVEST) study.

Potential New Anti-Inflammatory Drug for Type 2 Diabetes
Posted: Sunday, March 28, 2010
An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research.

Postprandial Hyperglycemia and Increased Cardiovascular Risk
Posted: Sunday, March 21, 2010
Hyperglycemia is a major risk factor for both the microvascular and macrovascular complications in patients with Type 2 diabetes. This review summarizes the cardiovascular results of large outcomes trials in diabetes and presents new evidence on the role of hyperglycemia, with particular emphasis on postprandial hyperglycemia, in adverse cardiovascular outcomes in patients with Type 2 diabetes.

A1c's Over Five Percent Increase Risk for Stroke
Posted: Sunday, March 14, 2010
Glycated hemoglobin (HbA1c), even at levels considered in the "normal" range, emerged as an independently significant predictor of heart-disease events, stroke, and death over more than a decade in an analysis from the Atherosclerosis Risk in Communities (ARIC) study. The risks of incident diabetes, coronary heart disease events, and death were significantly increased for all HbA1c values higher than the reference range of 5.0% to <5.5%.

Different Oral Antidiabetics Associated with Different Adverse Outcomes?
Posted: Sunday, March 07, 2010
Risk of cardiovascular disease and all-cause mortality among patients with Type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database.

FDA Reviewers Urge Pulling Rosiglitazone
Posted: Sunday, February 28, 2010
Two FDA reviewers have recommended that the diabetes drug rosiglitazone (Avandia) be pulled from the market because of its link to major cardiac events.

High Levels of Protein in Urine Associated with Increased Risk of Death, Heart Attack and Kidney Failure
Posted: Sunday, February 14, 2010
Patients with high levels of proteinuria (protein in urine) in addition to another marker of reduced kidney function had an associated increased risk of all-cause death, heart attack or progression to kidney failure, according to a study.

Severe Complications of Diabetes Higher in Patients with Major Depression
Posted: Sunday, February 14, 2010
Major depression raises risks of advanced and severe complications from diabetes, according to a prospective study. These complications include kidney failure or blindness, the result of small vessel damage, as well as major vessel problems leading to myocardial infarction (MI) or stroke.

US Health-Risk Surveillance Results
Posted: Sunday, February 14, 2010
Results from January 2007 to December 2007 from the Behavioral Risk Surveillance System (BRFSS), an ongoing telephone survey of US adults on health-risk behaviors and the use of preventative healthcare services related to the leading causes of death and disability in the United States, were reported last week.

Overeating Destroys Normal Metabolism and Sets Stage for Diabetes
Posted: Sunday, February 14, 2010
Overeating triggers a molecule once considered to be only involved in detecting and fighting viruses to also destroy normal metabolism, leading to insulin resistance and setting the stage for diabetes.

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