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Drugs » Januvia

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FDA Approves Diabetes and Cholesterol-Lowering Drug Combo: Juvisync®
Posted: Sunday, October 09, 2011
Known as Juvisync (Merck), the new medication combines sitagliptin (Januvia, Merck), a dipeptidyl peptidase-4 (DPP-4) inhibitor used for glycemia control, with the cholesterol-lowering simvastatin.

FDA Approves New DPP-IV Inhibitor: Tradjenta (Linagliptin)
Posted: Sunday, May 08, 2011
A new prescription medication Tradjenta (linagliptin) has gained FDA approval for the treatment of adult Type 2 diabetes. Tradjenta will compete with two other drugs in the same family, Onglyza and Januvia.

Search for Diabetes "Cure" Focuses on Beta-Cell Regeneration
Posted: Tuesday, December 28, 2010
A simple strategy of just combining two FDA approved drugs (Januvia® + Prevacid®) may restore normoglycemia.

EASD: Pioglitazone-Sitagliptin Combination Achieves Durable Glycemic Control
Posted: Sunday, October 03, 2010
Adding 50 mg of sitagliptin (Januvia) to pioglitazone (Actos) allowed patients with Type 2 diabetes to achieve sustained glycemic control, a yearlong trial showed.

FDA Issues Caution for Januvia and Janumet for Acute Pancreatitis
Posted: Wednesday, September 30, 2009
U.S. health officials said on Friday they suspect Merck & Co., Inc.'s blockbuster diabetes drug Januvia may be linked to serious cases of inflamed pancreas, but company officials disputed the connection.

DPP-IV Inhibitors and Increased GLP-1 Levels May Increase Pancreatitis Risk -- Metformin Can Negate Adverse Effects
Posted: Tuesday, May 12, 2009
A drug widely used to treat Type 2 diabetes may have unintended effects on the pancreas that could lead to a form of low-grade pancreatitis in some patients and a greater risk of pancreatic cancer in long-term users, according to researchers at UCLA , but the adverse effects can be negated when combined with an older diabetes drug.

Type 2 Diabetes Drug Increases Pancreatitis and Pancreatic Cancer Risk
Posted: Wednesday, May 06, 2009
A common drug used to lower blood sugar in type 2 diabetics has been observed to increase risk of pancreatitis, and is believed to also increase long-term pancreatic cancer risk.

EASD: Byetta Wins In Head to Head Trial Over Januvia In Postprandial Glucose
Posted: Wednesday, September 17, 2008
In a month-long head-to-head trial, the incretin mimetic exenatide (Byetta) reduced postprandial glucose in type 2 diabetes more than did sitagliptin (Januvia), an oral DPP-4 inhibitor, researchers reported.

Januvia/Byetta Becoming First and Second-Line Therapy for Type 2 Diabetes
Posted: Wednesday, September 10, 2008
New research reports that Januvia is currently prescribed most often as a third- or later-line of therapy for the treatment of type 2 diabetes.

Sitagliptin (Januvia) Plus a Sulfonylurea Increases Risk for Hypoglycemia
Posted: Wednesday, February 27, 2008
The FDA approved safety labeling revisions for sitagliptin tablets (Januvia; Merck & Co, Inc) to advise of the risk for hypoglycemia.

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