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Drugs » Metformin

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Rosiglitazone Plus Metformin Prevents Bone Loss
Posted: Wednesday, June 24, 2009
Recent research shows that rosiglitazone decreases bone mineral density in healthy humans and appears to increase fractures in women with Type 2 diabetes, compared with those receiving metformin or another diabetes medication.

Cancer Patients May Benefit from Diabetic Drug
Posted: Saturday, June 20, 2009
Metformin, a widely used anti-diabetic drug, has the effect of making cancer therapies and vaccines more effective by boosting the immune system, according to a recently published study.

Exenatide Improves Beta-Cell Function Compared with Insulin Glargine
Posted: Wednesday, June 03, 2009
Over a 1-year period, treatment with exenatide improved beta-cell function significantly more, and led to greater weight loss, than did insulin glargine, in a study of patients with Type 2 diabetes who had previously been treated with metformin.

New Information on how Metformin Works
Posted: Tuesday, May 26, 2009
Not only has new research told us how metformin really works, but a new biomarker was found that can determine the optimal dose of metformin that should be used to get the best results for each patient.

CHMP Recommends Approval of Novo Nordisk's Victoza(R) (Liraglutide) for Type 2 Diabetes
Posted: Wednesday, May 20, 2009
Novo Nordisk announces that the Committee for Medicinal Products for Human Use (CHMP), under the European Medicines Agency (EMEA) adopted a positive opinion, recommending marketing authorization, for Victoza® for the treatment of Type 2 diabetes.

DPP-IV Inhibitors and Increased GLP-1 Levels May Increase Pancreatitis Risk -- Metformin Can Negate Adverse Effects
Posted: Tuesday, May 12, 2009
A drug widely used to treat Type 2 diabetes may have unintended effects on the pancreas that could lead to a form of low-grade pancreatitis in some patients and a greater risk of pancreatic cancer in long-term users, according to researchers at UCLA , but the adverse effects can be negated when combined with an older diabetes drug.

Combo of Diabetes Drugs Increases Mortality
Posted: Thursday, August 21, 2008
Combination treatment for type 2 diabetes using two classes of drugs -- metformin and sulfonylureas -- may increase the risk of hospitalization for cardiovascular disease and mortality, according to a new report.

Endos Issue Consensus Statement on Pre-Diabetes
Posted: Wednesday, July 30, 2008
It is good to see that there is more concern for those at risk for diabetes. The treatment of pre-diabetes requires intensive lifestyle modification and the use of metformin and acarbose for controlling glycemia for high-risk patients, declared a consensus statement issued by the American College of Endocrinology task force.

Metformin Cost Effective in Preventing Diabetes
Posted: Thursday, January 10, 2008
According to recent research published in the journal Diabetes Care, "In the Indian Diabetes Prevention Program (IDPP), a 3-year randomized, controlled trial, lifestyle modification (LSM) and metformin helped to prevent type 2 diabetes in subjects with impaired glucose tolerance (IGT).

Insulin and Not Metformin is Linked to Higher Rate of Fractures
Posted: Thursday, December 06, 2007
Insulin-sensitizing treatment with metformin is not associated with a higher incidence of bone fractures, but current treatment with insulin increases the risk for fractures, according to the results of a nested case-control study.

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