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Drugs » Metformin

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Mortality Lower with Metformin
Posted: Sunday, July 04, 2010
Metformin use may reduce mortality by 33% among patients with Type 2 diabetes who are at risk for cardiovascular events, researchers say.

First-in-Class Novel Drug Lowers Blood Glucose and Weight
Posted: Sunday, July 04, 2010
In early trials, a novel sodium glucose co-transporter 2 (SGLT2) inhibitor appears to improve glycemic control and reduce weight among patients on metformin, researchers reported.

Antioxidants Increase Insulin Sensitivity
Posted: Sunday, June 27, 2010
A diet high in antioxidants may help increase insulin sensitivity and enhance the effects of metformin, according to a small study.

Metformin-induced Vitamin B12 Deficiency Presenting as a Peripheral Neuropathy
Posted: Tuesday, May 04, 2010
Chronic metformin use results in vitamin B12 deficiency in 30% of patients. Exhaustion of vitamin B12 stores usually occurs after twelve to fifteen years of absolute vitamin B12 deficiency.

Early Treatment Doubles Chance of Success for People with Diabetes
Posted: Sunday, March 21, 2010
Results from the first study that compares failure rates of Metformin in real-world setting are out.

Stinky Diabetes Drug May Result in Poor Adherence
Posted: Sunday, March 14, 2010
An immediate-release form of the antidiabetic agent metformin has a dead fish odor that may cause patients to stop taking the drug, clinicians warned.

Lasting Benefit Seen for Lifestyle Changes, Metformin in Diabetes
Posted: Sunday, February 28, 2010
For people at risk for Type 2 diabetes, a combination of diet, exercise and, to a lesser extent, treatment with metformin can help keep the disease at bay for 10 years, researchers said.

Use of Metformin in Type 1's
Posted: Sunday, February 14, 2010
Metformin reduces insulin-dose requirement in Type 1 diabetes. As adding metformin to insulin therapy has been advocated in Type 1 diabetes, researchers at the Universities of Dundee and Aberdeen, U.K., conducted a systematic review of published clinical trials and clinical trial databases to assess the effects on HbA1c, weight, insulin-dose requirement and adverse effects.

Metformin Decreases BMI in Pre-Diabetic Adolescents
Posted: Sunday, February 14, 2010
Metformin XR (extended release formulation) appears to cause a decrease in body mass index (BMI) in non-diabetic obese adolescents when combined with a lifestyle intervention program.

Preventing Diabetes for Ten Years Plus
Posted: Sunday, February 14, 2010
Ten-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study.

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