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Research » Drugs

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Lipid-lowering Therapy Prevents Coronary Events in Diabetics
Posted: Friday, June 02, 2006
Lipid-lowering drug treatment significantly reduced the risk of major coronary events in patients with and without type 2 diabetes, and that patients with diabetes derived more benefit from lipid-lowering therapy as primary and secondary prevention.



Oral Contraceptive Use Protects Against Coronary Disease Later in Life
Posted: Friday, June 02, 2006
In postmenopausal women undergoing coronary angiography for suspected myocardial ischemia, past oral contraceptive use is tied to less atherosclerotic disease, according to a new study.



Ghrelin Involved in Development of Diabetes
Posted: Tuesday, May 30, 2006
Ghrelin, a hormone long considered a key player in obesity, may instead take a major role in maintaining the balance between insulin and glucose and the development of diabetes.



Bristol-Myers Squibb Discontinues Development of Pargluva
Posted: Tuesday, May 30, 2006
Researchers at the Cleveland Clinic found that Pargluva could double the risk of death, heart attack or strokes in diabetics compared to a placebo.



Grapefruit Juice Drug Interaction Culprit Identified
Posted: Wednesday, May 24, 2006
Those dangerous interactions when grapefruit juice is mixed with some drugs are apparently triggered by members of a family of plant toxins called furanocoumarins. Watch for the new Grapefruit juice to hit the supermarket shelves soon.


Scientists Make Major Finding on Potential Cure for Type 1 Diabetes
Posted: Monday, May 15, 2006
The study, which combined two therapies (anti-CD3 antibody and proinsulin peptide) already being tested individually in human clinical trials, produced better efficacy, longer-lasting results and fewer side effects in the preclinical trials in mice than either therapy has shown alone in the human studies. The researchers hope to begin testing the combination therapy in human clinical trials later this year.



Dynamic Duo, Combination Therapy Reverses Type 1 Diabetes
Posted: Monday, May 15, 2006
By combining an oral with an intranasal therapy for type 1 diabetes that have individually shown beneficial, but limited, effects in previous studies, Matthias von Herrath and colleagues at the La Jolla Institute for Allergy and Immunology deliver a one-two punch, and prove that, in this case, 2 treatments work together better than one.



Plavix-Aspirin Combo No Better than Aspirin Alone for CVD Event Reduction
Posted: Friday, March 24, 2006
The CHARISMA trial of aspirin alone vs. aspirin plus Plavix (clopidogrel) showed no benefit over aspirin alone at preventing major cardiovascular events or death.

In addition to finding no significant benefit for the combination in a randomized trial in more than 15,000 patients, Plavix plus aspirin for patients with multiple risk factors was associated with increased risk for moderate and serious bleeding

Chromium Picolinate Helps Muscles Use Blood Sugar
Posted: Friday, February 24, 2006
A new published study: it is reported that chromium prompts muscles to become more efficient. Researchers found that daily use of chromium picolinate enhanced muscle sensitivity to insulin in obese, insulin-resistant rats.

New Diabetes Drugs In the Pipeline
Posted: Thursday, February 16, 2006
Six new pharma treatment strategies in controlling diabetes.

The complexity of glucose metabolism and the number of cellular processes affected by diabetes provides ample space for new drug targets and for first-in-class molecules. Some of them have reached or are close to early clinical development in type 2 diabetes.

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