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Research » Drugs

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Newborn Period Crucial Time Window to Prevent Later Diabetes
Posted: Sunday, November 06, 2011
A new approach to prevent type 2 diabetes may be on the horizon. The use of exendin-4 in newborns may prevent diabetes later in life.

Diabetes Drug Also Reduces Inflammation
Posted: Saturday, November 05, 2011
A GLP-1 drug prescribed to help patients with type 2 diabetes improve blood-sugar control also has a powerful anti-inflammatory effect, and the effect was observed within 2 hours following a single dose.

Pyridoxamine May Slow Early Diabetic Nephropathy
Posted: Saturday, November 05, 2011
Pyridoxamine (vitamin B6) is known to be an effective scavenger of reactive oxygen species and a potent inhibitor of advanced glycation end products. A new study demonstrated the benefits for patients with Type 2 diabetes.

Diabetes Medication Compliance a Major U.S. Issue
Posted: Sunday, October 23, 2011
We need to do a better job. Research by the New England Healthcare Institute shows that patients who don't take their medications as prescribed, cost the U.S. health care system an estimated $290 billion in avoidable medical spending each year.

FDA Approves Diabetes and Cholesterol-Lowering Drug Combo: Juvisync®
Posted: Sunday, October 09, 2011
Known as Juvisync (Merck), the new medication combines sitagliptin (Januvia, Merck), a dipeptidyl peptidase-4 (DPP-4) inhibitor used for glycemia control, with the cholesterol-lowering simvastatin.

New First in Class Glucagon Antagonists Show Promise for Diabetes
Posted: Sunday, September 25, 2011
New data on two investigational glucagon receptor antagonists suggest that this novel class of drugs has potential to be an effective treatment for type 2 diabetes.

Intensified Treatment with Basal Insulin Improves Control and Weight Loss
Posted: Saturday, September 24, 2011
Adding insulin detemir to a treatment regimen of metformin and liraglutide improved glycemic control and led to sustained weight loss for up to 52 weeks in patients with type 2 diabetes.

EASD: Outpatient Test Discriminates MODY from Type 1 Diabetes
Posted: Saturday, September 24, 2011
A measure of the postprandial ratio of urinary C-peptide to creatinine (UCPCR) can distinguish maturity-onset diabetes of the young (MODY) from type 1 diabetes mellitus, allowing some children who would otherwise be treated with insulin to receive oral antidiabetic agents alone.

EASD: Twice-Daily Aspirin Betters Platelet Inhibition for People with Diabetes
Posted: Monday, September 19, 2011
Twice-daily aspirin administration, but not a once-daily doubling of the dose, appears to provide good inhibition of platelet cyclooxygenase (COX)-1 in diabetic patients who have rapid recovery of COX-1 activity, and might enhance cardiovascular protection.

EASD: First Injection-free Once-A-Year GLP-1
Posted: Sunday, September 18, 2011
ITCA 650, injection-free continuous delivery of GLP-1 therapy, demonstrated significant and sustained reductions in HbA1c and body weight over 48 weeks of treatment with a marked reduction in the GI AEs typically associated with this class.

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