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Research » Complications

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Postprandial Hyperglycemia and Increased Cardiovascular Risk
Posted: Sunday, March 21, 2010
Hyperglycemia is a major risk factor for both the microvascular and macrovascular complications in patients with Type 2 diabetes. This review summarizes the cardiovascular results of large outcomes trials in diabetes and presents new evidence on the role of hyperglycemia, with particular emphasis on postprandial hyperglycemia, in adverse cardiovascular outcomes in patients with Type 2 diabetes.

Eye Disease Linked to Weakened Brain Power in People with Diabetes
Posted: Sunday, March 21, 2010
Diabetic retinopathy, the leading cause of blindness in the working-age population, could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research.

High Cholesterol, Diabetes Lead Drug Spending for the Elderly
Posted: Sunday, March 21, 2010
Purchases of cholesterol and diabetes prescription drugs by elderly Medicare beneficiaries reached nearly $19 billion in 2007 -- about one-fourth of the approximately $82 billion spent for medications for the elderly, according to the latest AHRQ News and Numbers.

Special Newsflash: Exenatide Once Weekly -- FDA Update
Posted: Tuesday, March 16, 2010
Amylin, Lilly and Alkermes received a Complete Response Letter from FDA for Exenatide Once Weekly. New drug to be called BYDUREON (exenatide for extended-release injectable suspension).

In the complete response letter there are no requests for new pre-clinical or clinical trials. Requests raised in the letter primarily relate to the finalization of the product labeling with accompanying Risk Evaluation and Mitigation Strategy (REMS) and clarification of existing manufacturing processes.

A1c's Over Five Percent Increase Risk for Stroke
Posted: Sunday, March 14, 2010
Glycated hemoglobin (HbA1c), even at levels considered in the "normal" range, emerged as an independently significant predictor of heart-disease events, stroke, and death over more than a decade in an analysis from the Atherosclerosis Risk in Communities (ARIC) study. The risks of incident diabetes, coronary heart disease events, and death were significantly increased for all HbA1c values higher than the reference range of 5.0% to <5.5%.

Stinky Diabetes Drug May Result in Poor Adherence
Posted: Sunday, March 14, 2010
An immediate-release form of the antidiabetic agent metformin has a dead fish odor that may cause patients to stop taking the drug, clinicians warned.

TZD Patients Are 50% More Likely to Develop Bone Fractures
Posted: Sunday, March 07, 2010
A Henry Ford Hospital study finds women with Type 2 diabetes who take a commonly prescribed class of medications called TZD's to treat insulin resistance may be at a higher risk for developing bone fractures within 1 year of taking the medication.

Celiac and Diabetes Are Related Through Genetics
Posted: Sunday, March 07, 2010
Data increasingly supports an association between rs6822844 at the IL2-IL21 region and multiple autoimmune diseases in individuals of European descent. A number of autoimmune diseases share susceptibility genes, pointing to similar molecular mechanisms.

Stress Affects Brain Function in Older People with Type 2 Diabetes
Posted: Sunday, March 07, 2010
According to researchers from the University of Edinburgh, UK, stress increases the risk of memory loss and cognitive decline in older people with Type 2 diabetes.

Birthplace Weighs Heavily on Immigrant Weight and Risk for Diabetes
Posted: Sunday, March 07, 2010
Where a US immigrant was born could play a significant role in how many pounds they pack on after arriving in America, according to a new study.

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