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Research » Transplants

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Experimental Artificial Pancreas Succeeds with Type 1 Diabetes Patients
Posted: Tuesday, April 27, 2010
In the first clinical trial of a system using two hormones, an artificial pancreas delivered insulin and glucagon in a way that closely mimics the body's control of blood sugar and maintained near-normal levels of glucose in a small group of Type 1 diabetes patients without them developing hypoglycemia.

FDA Approves Combined Diabetes Management System
Posted: Sunday, March 28, 2010
The FDA approved Medtronic's MiniMed Paradigm REAL-Time Revel System, a diabetes management system that combines an insulin pump with a glucose monitoring system. The system may represent the next step toward an artificial pancreas.

Key to Reversing Type 1 Diabetes Discovered
Posted: Sunday, February 14, 2010
Doctors at Eastern Virginia Medical School's Strelitz Diabetes Center have been stalking the culprit responsible for Type 1 diabetes. Now, they are one step closer.

Artificial Pancreas Improves Glucose Control
Posted: Sunday, February 14, 2010
Closed-loop insulin delivery systems can improve overnight blood sugar control and reduce hypoglycemia risk in young patients with Type 1 diabetes, researchers have found.

New GLP-1 Medication Lowers A1c Six Months after Treatment Stopped
Posted: Sunday, February 07, 2010
Transition Therapeutics announces results of a Phase 2 study of TT-223 (GLP-1 Cpd + Gastrin) in Type 2 diabetes patients. The results show that beta-cells can possibly be generated and/or restored. After a 10 week trial the drug was stopped and 6 months later, the A1c had dropped by 1.13 points.

JDRF Artificial Pancreas Project Going Forward
Posted: Sunday, January 24, 2010
RF forms partnership with Animas to develop first-generation automated system for managing Type 1 diabetes.

Joslin Identifies Source of Beta Cell Damage
Posted: Sunday, January 17, 2010
Scientists at the Joslin Diabetes Center, Boston, MA, led by Principal Investigator Robert Stanton, M.D., have discovered that high blood glucose levels damage a key enzyme that guards insulin-producing beta cells. Their surprising finding raises hopes of finding drugs that protect the enzyme, and thus the beta cells and their insulin production. The discovery focuses on a cellular process known as "oxidative stress."

Andrew P. Mandell - Mr. Diabetes® to Sit On ProtoKinetix Advisory Board
Posted: Friday, January 15, 2010
Andrew P. Mandell - Mr. Diabetes®, Executive Director of Defeat Diabetes Foundation and diabetes advocate announced today that he will be sitting on the ProtoKinetix (PKTX) Advisory Board. ProtoKinetix, Inc. is a biotechnology company that has developed and patented a family of synthetic anti-aging glycoproteins (AAGP™) for medicine and the biotechnology and cosmetic industries.

ProtoKinetix’ AAGP™ Shows Promise as a Tool in Diabetes Treatment / Cure
Posted: Tuesday, January 12, 2010
Independent studies done by universities and corporations have illustrated a remarkable increase in the yield of viable stem cells after cryopreservation using AAGP™ in the freeze-thaw process. One future approach to increasing diabetics’ insulin production is related to an ability to convert their stem cells into islet cells for transplantation. The feasibility of this procedure is dependent upon the amount of functioning islet cells that can be derived from the patient’s stem cells. This is where AAGP™ can make a very beneficial contribution.

First Pancreas Removal and Islet Cell Transplantation Performed
Posted: Sunday, December 20, 2009
A 21-year old airman severely wounded in Afghanistan is recovering at Walter Reed Army Medical Center, Bethesda, MD, after several surgeries and an unprecedented transplant.

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