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Use of Metformin in Type 1's
Posted: Sunday, February 14, 2010
Metformin reduces insulin-dose requirement in Type 1 diabetes. As adding metformin to insulin therapy has been advocated in Type 1 diabetes, researchers at the Universities of Dundee and Aberdeen, U.K., conducted a systematic review of published clinical trials and clinical trial databases to assess the effects on HbA1c, weight, insulin-dose requirement and adverse effects.

High Levels of Protein in Urine Associated with Increased Risk of Death, Heart Attack and Kidney Failure
Posted: Sunday, February 14, 2010
Patients with high levels of proteinuria (protein in urine) in addition to another marker of reduced kidney function had an associated increased risk of all-cause death, heart attack or progression to kidney failure, according to a study.

Metformin Decreases BMI in Pre-Diabetic Adolescents
Posted: Sunday, February 14, 2010
Metformin XR (extended release formulation) appears to cause a decrease in body mass index (BMI) in non-diabetic obese adolescents when combined with a lifestyle intervention program.

Normal Glucose Greater than 85mg/dL in Kids Predicts Diabetes Later
Posted: Sunday, February 14, 2010
Increases in fasting plasma glucose during childhood -- even though levels remain in the normal range 85-100mg/dL.) -- can predict adult prediabetes and Type 2 diabetes later in life, a retrospective cohort study showed.

Preventing Diabetes for Ten Years Plus
Posted: Sunday, February 14, 2010
Ten-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study.

Severe Complications of Diabetes Higher in Patients with Major Depression
Posted: Sunday, February 14, 2010
Major depression raises risks of advanced and severe complications from diabetes, according to a prospective study. These complications include kidney failure or blindness, the result of small vessel damage, as well as major vessel problems leading to myocardial infarction (MI) or stroke.

Artificial Pancreas Improves Glucose Control
Posted: Sunday, February 14, 2010
Closed-loop insulin delivery systems can improve overnight blood sugar control and reduce hypoglycemia risk in young patients with Type 1 diabetes, researchers have found.

US Health-Risk Surveillance Results
Posted: Sunday, February 14, 2010
Results from January 2007 to December 2007 from the Behavioral Risk Surveillance System (BRFSS), an ongoing telephone survey of US adults on health-risk behaviors and the use of preventative healthcare services related to the leading causes of death and disability in the United States, were reported last week.

Overeating Destroys Normal Metabolism and Sets Stage for Diabetes
Posted: Sunday, February 14, 2010
Overeating triggers a molecule once considered to be only involved in detecting and fighting viruses to also destroy normal metabolism, leading to insulin resistance and setting the stage for diabetes.

Caloric Restriction with or without Exercise: The Fitness versus Fatness Debate
Posted: Sunday, February 14, 2010
There is a debate over the independent effects of aerobic fitness and body fatness on mortality and disease risks.

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