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Self-Management » A1c

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Special Newsflash: Exenatide Once Weekly -- FDA Update
Posted: Tuesday, March 16, 2010
Amylin, Lilly and Alkermes received a Complete Response Letter from FDA for Exenatide Once Weekly. New drug to be called BYDUREON (exenatide for extended-release injectable suspension).

In the complete response letter there are no requests for new pre-clinical or clinical trials. Requests raised in the letter primarily relate to the finalization of the product labeling with accompanying Risk Evaluation and Mitigation Strategy (REMS) and clarification of existing manufacturing processes.

A1c's Over Five Percent Increase Risk for Stroke
Posted: Sunday, March 14, 2010
Glycated hemoglobin (HbA1c), even at levels considered in the "normal" range, emerged as an independently significant predictor of heart-disease events, stroke, and death over more than a decade in an analysis from the Atherosclerosis Risk in Communities (ARIC) study. The risks of incident diabetes, coronary heart disease events, and death were significantly increased for all HbA1c values higher than the reference range of 5.0% to <5.5%.

Stinky Diabetes Drug May Result in Poor Adherence
Posted: Sunday, March 14, 2010
An immediate-release form of the antidiabetic agent metformin has a dead fish odor that may cause patients to stop taking the drug, clinicians warned.

New Gestational Diabetes Guidelines Find More Women at Risk
Posted: Sunday, March 07, 2010
New blood sugar measurements used to determine gestational diabetes will mean that lower levels may pose risks for mother and baby.

Different Oral Antidiabetics Associated with Different Adverse Outcomes?
Posted: Sunday, March 07, 2010
Risk of cardiovascular disease and all-cause mortality among patients with Type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database.

Diabetes Diagnosis to Soar with A1c Switch for Diagnosis
Posted: Sunday, March 07, 2010
European authorities are considering changing the diabetes diagnostic criteria (using the A1c test) in a move that could almost double the number of people classed as having the disease.

LifeScan Recalls Specific Lots of Consumer and Professional OneTouch® SureStep® Test Strips Due To Inaccurate Readings at High Levels
Posted: Friday, February 26, 2010
LifeScan, Inc. is conducting a voluntary recall in the United States of eight lots of OneTouch® SureStep® Test Strips, used by people with diabetes to measure their blood glucose levels at home. The test strips are being recalled because they may provide falsely low glucose results when the glucose level is higher than 400 mg/dL.

Diabetes Tied to Poor Impulse Control
Posted: Sunday, February 21, 2010
Patients with newly diagnosed Type 2 diabetes were significantly more likely to show poor impulse control in psychological testing than healthy people, researchers said. The findings could help explain why diabetic patients find it difficult to make the recommended lifestyle adjustments such as avoiding high-fat foods and maintaining daily exercise.

Vinegar Decreases Postprandial Hyperglycemia in Patients with Type 1
Posted: Sunday, February 21, 2010
Vinegar could be easily used as a complementary food (e.g., in a salad dressing) to reduce hyperglycemia.

Aggressive Treatment for Type 2's Should Begin at Diagnosis
Posted: Sunday, February 14, 2010
A year and a half ago, San Antonio's Dr. Ralph DeFronzo stood before thousands of doctors and told them the way most treat their diabetic patients just doesn't work very well and we need to be more aggressive. What we are doing now is just not working. A lengthy paper signed by DeFronzo and 15 other diabetes experts from the United States and Europe, slated for publication, also argues against the current ADA guidelines.

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