Treating Pre-Diabetes with Increased Fiber
Consumption To Prevent Diabetes
posted 07/10/03
High intake of dietary fiber is
associated with enhanced insulin sensitivity.
The purpose of the study was to examine cross-sectional associations of dietary
fiber intake with insulin resistance, insulin secretion, and glucose tolerance
in a population at high risk for type 2 diabetes.
The subjects consisted of 248 male and 304 female adult nondiabetic relatives of
patients with type 2 diabetes. Dietary intake was measured by means of two 3-day
food records. Associations of total, water-insoluble, and water-soluble fiber
with measures of glucose metabolism based on an oral glucose tolerance test,
were analyzed by multiple linear regression analysis adjusting for sex, age,
length of education, physical activity, BMI, waist-to-hip ratio, systolic blood
pressure, and serum triglyceride and HDL cholesterol concentrations. The
homeostasis model assessment insulin resistance index, the incremental 30-min
serum insulin concentration divided by the incremental 30-min glucose
concentration, and fasting and 2-h glucose concentrations were the outcome
variables.
The results showed that the dietary intake of total as well as water-insoluble
and water-soluble fiber was inversely associated with insulin resistance: -0.17
(0.07), P = 0.012; -0.15 (0.07), P = 0.024; and -0.14 (0.07), P = 0.049
[regression coefficients (SE)]. Fiber variables were unrelated to insulin
secretion and plasma glucose concentrations.
In conclusion, the results support evidence that a high intake of dietary fiber
is associated with enhanced insulin sensitivity and therefore may have a role in
the prevention of type 2 diabetes.
Source: Diabetes In Control Dot Com: Associations of
Dietary Fiber With Glucose Metabolism in Nondiabetic Relatives of Subjects With
Type 2 Diabetes
The Botnia Dietary Study : Diabetes Care 26:1979-1985, 2003.
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