New Oral Drug For Type 2
Diabetes
posted February 3,
2005
It enhances the action of insulin
and improves the control of blood glucose levels."
A Melbourne research team has invented an oral drug for diabetes sufferers in a
bid to given them a new lease of life. While Type 2 diabetes sufferers depend on
routine insulin injections and other therapies, the new drug could improve
insulin potency, lower blood glucose levels and reduce side effects.
The drug, ISF402, is the brainchild of Monash University diabetes experts Paul
Zimmet and Frank Ng.
Professor Zimmet said the drug's major advantage over existing therapies was
that it was based on a peptide in human fluids with four amino acids.
"ISF402 lowers blood glucose and has been shown to be more effective when
co-administered with injected insulin," Professor Zimmet said.
"It is anticipated that it will also enhance the action of insulin and improve
the control of blood glucose levels."
An oral version of the drug is being developed and human trials are scheduled
for the end of 2006. Monash studies have shown that the drug reduces glucose
levels in animal models of diabetes.
Professor Zimmet said the drug was targeted to Type 2 diabetes sufferers, whose
conditions were mostly linked to obesity and usually resistant to insulin.
Source: Diabetes In Control.com.
February 2005 News Article Index