Diabetes Treatment Approved
posted 12/02/02
The Food and Drug Administration has approved a drug for type 2
diabetes, a disease that affects some 15 million Americans.
The medication is called Metaglip(TM) HCl Tablets. Metaglip
is a combination of metformin and glipizide -- the two most
widely prescribed oral antidiabetic drugs. In clinical trials,
Metaglip was shown to be more effective in controlling the
blood sugar of type 2 diabetics than either metformin or glip-
izide used alone. Metaglip treats the primary defects underly-
ing type 2 diabetes -- relative insulin deficiency and insulin
resistance, researchers said. The drug combines glipizide and
metformin HCl -- two widely prescribed oral antidiabetic agents
-- in a single pill. The agents work in complementary fashion
to improve blood sugar in patients. Peter Dolan, chief execu-
tive officer and chairman of Bristol-Myers Squibb said,
"Metaglip represents an important new therapeutic choice for
the management of type 2 diabetes." In rare cases, Metaglip,
Glucovance and Glucophage XR may cause lactic acidosis (build-
up of lactic acid in the blood), which is serious and can be
fatal in half the cases. This occurs mainly in people whose
kidneys are not functioning properly, researchers said.
Source: United Press International.
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