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Blood Glucose Spikes
Impair Mental Function
posted October 21, 2004
Among patients with type 2 diabetes,
cognitive function is impaired and mood state deteriorates during acute
hyperglycemia.
Dr. Brian M. Frier, of Royal Infirmary of Edinburgh, UK, and colleagues examined
the effects of acute hyperglycemia in 20 patients with type 2 diabetes.
The participants were 61 years old on average and had diabetes for about 6
years. They were on various types of treatment, including antidiabetic
medication and insulin.
The team used a glucose infusion to produce optimal blood glucose levels or high
levels on two occasions. During this process, the researchers tested the
subjects' information processing ability, memory, and attention level.
During acute hyperglycemia, speed of information processing, working memory, and
some areas of attention were impaired. Acute hyperglycemia also adversely
affected mood, with reduced feelings of happiness and increased agitation,
anxiety, lethargy, and tiredness.
"The deleterious effects of hyperglycemia on cognitive function and mood states
may significantly interfere with many activities of daily living," Frier's group
concludes. These effects may in turn affect patients' ability to comply with
strategies aimed at treating spikes in blood glucose that occur after meals.
Source: Diabetes In Control.com: Diabetes Care, October 2004.
October 2004 News Article Index
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