Pharmaceutical Care
Reduces Risk Factors in Type 2 Diabetes
posted April 21, 2005
A 12-month pharmaceutical care
program can reduce vascular risk factors in patients with type 2 diabetes.
Pharmaceutical care involves the detection, prevention, and resolution of
drug-related problems, the authors explain, and has proved beneficial in other
chronic diseases, including asthma and cancer.
Dr. Timothy M. E. Davis from Fremantle Hospital in Western Australia and
colleagues investigated the impact of a pharmaceutical care program in a
community-based sample of 180 patients with type 2 diabetes who participated in
the program or received usual care.
Reductions in BMI, blood pressure, fasting plasma glucose, and glycosylated
hemoglobin were greater in patients participating in pharmaceutical care than in
the usual-care patients, the authors report. The pharmaceutical care group also
experienced nonsignificant improvements in serum lipid parameters and urine
albumin/creatinine ratios.
After controlling for greater use of ACE inhibitor/angiotensin 2 receptor
blocker therapy, antihypertensive drug use, and antiplatelet drug therapy in the
pharmaceutical care group, the researchers note, allocation to pharmaceutical
care remained an independent predictor of improvements in plasma glucose and
glycosylated hemoglobin.
The median 10-year risk of coronary heart disease decreased in the
pharmaceutical care group but did not change significantly in the usual-care
group, the results indicate. Similarly, the risk of stroke did not change for
the pharmaceutical care subjects but increased for the usual-care subjects.
"Our data and those of others argue that the pharmacist can be a beneficial
addition to integrated care for patients with type 2 diabetes," the
investigators add.
Source: Diabetes In Control.com: Diabetes Care 2005;28:771-776.
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