130 mmHg and/or
diastolic blood pressure (DBP)
85 mmHg.
The relation of CH and MH to the prevalence of these events was
examined.
posted 12/11/02
Elevations of HBP in the
morning in diabetic patients are strongly related to microvascular
and macrovascular complications.
Recently, repeated home blood pressure (HBP)
measurements in the morning for a long period have been shown to have
a stronger predictive power for mortality in patients with
hypertension than occasional casual/clinic blood pressure (CBP)
measurements. We studied whether HBP in the morning in type 2
diabetic patients is useful for prediction of diabetic complications.
The occurrence of diabetic complications (nephropathy,
retinopathy, coronary heart disease [CHD], and cerebrovascular
disease [CVD]) were examined in relation to morning HBP as well as to
CBP in 170 type 2 diabetic patients treated with antidiabetic and
antihypertensive drugs. Blood pressure was measured at the clinic
during the day and at home after awakening in the morning. Clinic
hypertension (CH) and morning hypertension (MH) were defined as
systolic blood pressure (SBP)
130 mmHg and/or
diastolic blood pressure (DBP)
85 mmHg.
The relation of CH and MH to the prevalence of these events was
examined.
The study showed that t here were no significant differences in
the prevalence of nephropathy, retinopathy, CHD, and CVD between the
two groups with (n = 131) and without CH (n = 39),
whereas the prevalence’s of these events in the patients with MH (n
= 97) were significantly higher (P < 0.05) than in those
without MH (n = 73). The prevalence of nephropathy was highly
associated with systolic MH.
From the results it was concluded that, e levations of HBP in the morning in diabetic patients are strongly related to microvascular and macrovascular complications, especially nephropathy. It is concluded that the control of MH may prevent vascular complications in type 2 diabetic patients.
Source: Diabetes In Control Dot Com: Diabetes Care 25:2218-2223, 2002.
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